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  1. Continuous venovenous rewarming : Results from a juvenile animal model.

    Article - En anglais

    Objective 

    To compare a standard and an experimental method of rewarming in 5-wk-old goats with induced moderate hypothermia.

    Design 

    Hypothermia was induced in ten juvenile Nubian goats.

    Five goats were randomly assigned to be rewarmed using standard techniques, and five were assigned to the experimental rewarming technique of a modified continuous venovenous hemofiltration circuit.

    Setting 

    Animal research facility, Greenville Hospital System/Clemson University Biomedical Cooperative, Clemson, S.C. Subjects : Ten 5-wk-old goats. interventions : Hypothermia to a body temperature of 29.4°C was induced in the goats.

    Each of the control group of five goats was rewarmed using standard methods.

    Each of the experimental group of five goats was rewarmed using a modified continuous venovenous hemofiltration circuit.

    Measurements and Main Results 

    At 2 hrs, the median temperature increase in the experimental group was 6.5°C, compared with an increase of only 1.5°C in the control group (p=02).

    The mean increase in core body temperature over time (from baseline to 150 mins) was also significantly greater in the experimental group (p=006).

    Conclusions 

    The use of a modified continuous venovenous hemofiltration circuit for rewarming in a juvenile goat model after induction of moderate hypothermia is more effective than are standard methods.

    Mots-clés Pascal : Hypothermie, Température corporelle, Réchauffement malade, Hémofiltration, Traitement, Efficacité traitement, Chèvre, Artiodactyla, Ungulata, Mammalia, Vertebrata, Animal jeune, Modèle animal, Epuration extrarénale

    Mots-clés Pascal anglais : Hypothermia, Body temperature, Patient warming, Hemofiltration, Treatment, Treatment efficiency, Goat, Artiodactyla, Ungulata, Mammalia, Vertebrata, Young animal, Animal model, Extrarenal dialysis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0068926

    Code Inist : 002B27B15. Création : 31/05/1999.