logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Has the mortality of septic shock changed with time ?

    Article - En anglais

    Objectives 

    To determine whether a systematic review of the literature could identify changes in the mortality of septic shock over time.

    Data Sources 

    A review of all relevant papers from 1958 to August 1997, identified through a MEDLINE search and from the bibliographies of articles identified.

    Data Synthesis 

    The search identified 131 studies (99 prospective and 32 retrospective) involving a total of 10,694 patients.

    The patients'mean age was 57 yrs with no change over time.

    The overall mortality rate in the 131 studies was 49.7%. There was an overall significant trend of decreased mortality over the period studied (r2=49, p<. 05).

    The mortality rate in those patients with bacteremia as an entry criterion was greater than that rate in patients whose entry criterion was sepsis without definite bacteremia (52.1% vs. 49.1% ; x2=6.1 and p<. 05).

    The site of infection altered noticeably over the years.

    Chest-related infections increased over time, with Gram-negative infections becoming proportionately less common.

    If all other organisms and mixed infections are included with the Gram-positives, the result is more dramatic, with these organisms being causative in just 10% of infections between 1958 and 1979 but in 31% of infections between 1980 and 1997.

    Conclusions 

    The present review showed a slight reduction in mortality from septic shock over the years, although this result should be approached with caution. (...)

    Mots-clés Pascal : Choc, Septique syndrome, Infection, Mortalité, Epidémiologie, Evolution, Taux, Pronostic, Homme, Revue bibliographique, Appareil circulatoire pathologie, Soin intensif

    Mots-clés Pascal anglais : Shock, Sepsis syndrome, Infection, Mortality, Epidemiology, Evolution, Rate, Prognosis, Human, Bibliographic review, Cardiovascular disease, Intensive care

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0068796

    Code Inist : 002B27B02. Création : 31/05/1999.