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  1. Study of erythrocytes, hemoglobin levels, and menstrual cycle characteristics of women exposed to aromatic hydrocarbons.

    Article, Communication - En anglais

    Medichem 1997 : Silver Jubilee Medichem Congress on Occupational and Environmental Health in the Chemical Industry. Varna, BGR, 1997/09/30.


    The impact of occupational hazards on erythrocyte and hemoglobin levels and menstrual cycle characteristics in women exposed to aromatic hydrocarbons was studied.

    The investigated cohort consisted of 110 women exposed to benzene, toluene, xylene and styrene while working in the transport and storage of petrochemical products (TSPP), the laboratory for the control of aromatic hydrocarbons (LCAH), and rubber and latex (RL) production at the biggest petrochemical plant in Bulgaria, Neftochim.

    Controls consisted of 45 women from the administrative personnel in the same plant.


    Questionnaires were administrated to all participants to obtain self-reported demographic data, data on characteristics of the menstrual cycle, and psychosomatic symptoms.

    Erythrocyte counts (RBC) and hemoglobin (HGB) levels were determined by the semiautomatic hematology analyzer Serono System 190.


    All subjects had signed an informed consent.


    The mean RBC counts and HGB levels of the women from the LCAH and TSPP departments were statistically significantly lower than those of the control group.

    We found statistically significant differences in all exposed groups in comparison with controls when the dose-response relationship was investigated. (...)

    Mots-clés Pascal : Exposition professionnelle, Médecine travail, Composé aromatique, Industrie pétrochimique, Homme, Femelle, Surveillance, Toxicité, Hématopoïèse, Cycle menstruel, Etude cohorte, Solvant organique, Relation dose réponse, Teneur air ambiant

    Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Aromatic compound, Petrochemical industry, Human, Female, Surveillance, Toxicity, Hematopoiesis, Menstrual cycle, Cohort study, Organic solvent, Dose activity relation, Ambient air concentration

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0067450

    Code Inist : 002B03L04. Création : 31/05/1999.