This preliminary investigation examined neuropsychological performance in a sample of human immunodeficiency virus (HIV) - positive and HIV-negative African-American women with a history of drug use.
The study population was comprised of 10 HIV-negative, 9 asymptomatic HIV-positive, 13 symptomatic HIV-positive, and 10 acquired immunodeficiency virus (AIDS) patients.
A neuropsychological battery designed to assess attention, psychomotor processing, verbal memory, and visual memory was administered to participants.
No evidence of HIV-related cognitive impairment was found in patients in the early stages of HIV infection.
Multivariate analyses of variance revealed significant deficits in psychomotor processing and verbal recall in persons with AIDS.
These individuals showed greater difficulty in tasks requiring maintained attention and performed poorly on measures of immediate and delayed verbal recall.
In contrast, HIV status was not related to visual memory, verbal recognition, or the number of errors made during a verbal recall task.
The pattern of cognitive deficits observed in persons with AIDS resembles that commonly associated with subcortical pathology.
The cognitive deficits observed were not related to depression or recentness of drug use.
Mots-clés Pascal : SIDA, Virose, Infection, Virus immunodéficience humaine, Lentivirus, Retroviridae, Virus, Facteur risque, Neuropsychologie, Trouble cognition, Association, Chimiothérapie, Questionnaire, Femelle, Noir américain, Evaluation, Homme, Etats Unis, Amérique du Nord, Amérique, Immunopathologie, Immunodéficit, Système nerveux pathologie, Psychopathologie, Psychiatrie
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Human immunodeficiency virus, Lentivirus, Retroviridae, Virus, Risk factor, Neuropsychologia, Cognitive disorder, Association, Chemotherapy, Questionnaire, Female, Black American, Evaluation, Human, United States, North America, America, Immunopathology, Immune deficiency, Nervous system diseases, Psychopathology, Psychiatry
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0064531
Code Inist : 002B05C02D. Création : 31/05/1999.