Baker's asthma and rhinitis are among the most frequent occupational respiratory disorders.
The aim of the study was to evaluate the frequency of work-related symptoms and the clinical relevance of sensitization to allergens in screened and symptomatic bakers.
Eighty-nine bakers participating in a screening study and 104 bakers filing a claim for compensation were examined with regard to occupational and clinical case history, lung function parameters, and sensitization to bakery allergens by skin prick tests, specific IgE analyses, and inhalative challenge tests.
A high prevalence of respiratory disorders, abnormal lung function parameters, and sensitization to bakery allergens exists.
Most frequently, bakers with workplace-related respiratory symptoms showed sensitization to wheat flour (64% rye flour (52%), soy bean flour (25%), and alpha-amylase (21%). The correlation between these sensitizations and asthma case history and inhalative challenge test responses was significant.
However, approximately 29% of the bakers with respiratory symptoms showed no sensitization to these bakery allergens, whereas 32% of the sensitized bakers in the screening group had no workplace-related symptoms.
Atopic status defined by skin prick test sensitization to common allergens or elevated total IgE levels was found to beta risk factor for the development of sensitization to bakery allergens and respiratory symptoms. (...)
Mots-clés Pascal : Asthme, Allergie, Boulangerie, Boulanger, Maladie professionnelle, Exposition professionnelle, Farine blé, Amylase, Enzyme, Farine seigle, Soja, Allergène, Etiologie, Prévalence, Homme, Etude transversale, Allemagne, Europe, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Immunopathologie, Médecine travail
Mots-clés Pascal anglais : Asthma, Allergy, Bakery, Baker, Occupational disease, Occupational exposure, Wheat flour, Amylase, Enzyme, Rye flour, Soybean, Allergen, Etiology, Prevalence, Human, Cross sectional study, Germany, Europe, Respiratory disease, Obstructive pulmonary disease, Immunopathology, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0061808
Code Inist : 002B06C02. Création : 31/05/1999.