In order to verify diphtheria immunity a seroepidemiological survey was performed in 1996-1997.
Serum samples were obtained from 501 subjects 14 years old, recruited at 8 schools in Rome, and from 490 subjects 20-30 years old recruited from 15 Italian regions.
Serum diphtheria antitoxin was titrated using the Vero cell assay.
The minimum protection level of antitoxin was set at 0.01 IU ml-1.
The results show that the younger population have a good immunity to diphtheria while a large proportion of young adults is devoid of protective levels of diphtheria antitoxin.
Out of the 501 subjects 14 years old.
495 (98.8%) had a diphtheria antitoxin titre >= 0.01 IU ml-1.
Only 6 (1.2%) teenagers were susceptible.
Out of the 490 subjects 20-30 years old, 109 (22.2%) were susceptible. 381 (77.8%) had a diphtheria antitoxin titre >= 0.01 IU ml-1.
The data stress for booster immunization at the end of junior high school.
Mots-clés Pascal : Diphtérie, Bactériose, Infection, Immunisation, Vaccination, Sérologie, Taux, Epidémiologie, Evaluation, Adulte jeune, Homme, Italie, Europe
Mots-clés Pascal anglais : Diphtheria, Bacteriosis, Infection, Immunization, Vaccination, Serology, Rate, Epidemiology, Evaluation, Young adult, Human, Italy, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0050738
Code Inist : 002B05A02. Création : 31/05/1999.