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  1. Fulltext. Declining seroprevalence in a Very Large HIV epidemic : Injecting drug users in New York City, 1991 to 1996.

    Article - En anglais

    Fulltext.

    Objectives

    This study assessed recent trends in HIV seroprevalence among injecting drug users in New York City.

    Methods

    We analyzed temporal trends in HIV seroprevalence from 1991 through 1996 in 5 studies of injecting drug users recruited from a detoxification program, a methadone maintenance program, research storefronts in the Lower East Side and Harlem areas, and a citywide network of sexually transmitted disease clinics.

    A total of 11 334 serum samples were tested.

    Results

    From 1991 through 1996, HIV seroprevalence declined substantially among subjects in all 5 studies : from 53% to 36% in the detoxification program, from 45% to 29% in the methadone program, from 44% to 22% at the Lower East Side storefront, from 48% to 21% at the Harlem storefront, and from 30% to 21% in the sexually transmitted disease clinics (all P<. 002 by X2tests for trend).

    Conclusions

    The reductions in HIV seroprevalence seen among injecting drug users in New York City from 1991 through 1996 indicate a new phase in this large HIV epidemic.

    Potential explanatory factors include the loss of HIV-seropositive individuals through disability and death and lower rates of risk behavior leading to low HIV incidence.

    Mots-clés Pascal : SIDA, Virose, Infection, Séropositivité, Virus immunodéficience humaine, Lentivirus, Retroviridae, Virus, Toxicomanie, Epidémiologie, Prévalence, Evolution, Homme, New York, Etats Unis, Amérique du Nord, Amérique, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Seropositivity, Human immunodeficiency virus, Lentivirus, Retroviridae, Virus, Drug addiction, Epidemiology, Prevalence, Evolution, Human, New York, United States, North America, America, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0048954

    Code Inist : 002B05C02D. Création : 31/05/1999.