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  1. Genetic testing for renal diseases : Medical and ethical considerations.

    Article - En anglais

    Advances in understanding the genetic basis of renal disorders will soon allow for the clinical use ot genetic diagnostic testing.

    In this article, we review renal diseases with a known genetic basis and the current methods available for genetic testing.

    We then examine the potential medical indications for genetic testing, with special attention to autosomal dominant polycystic kidney disease (ADPKD).

    Because clinicians will be faced with patients considering genetic testing, we review the ethical considerations regarding genetic testing for renal diseases, recent genetic privacy legislation, and the special role genetic testing may have in transplantation.

    We conclude with a review of the necessary elements of informed consent, which provides the ethical foundation for patients deciding about genetic testing with the assistance of their physicians.

    Mots-clés Pascal : Rein polykystique, Déficit, Gène, Diagnostic, Maladie héréditaire, Indication, Ethique, Législation, Don organe, Conseil génétique, Consentement éclairé, Article synthèse, Homme, Appareil urinaire pathologie, Rein pathologie, Tumeur bénigne, Kyste, Génétique

    Mots-clés Pascal anglais : Polycystic kidney, Deficiency, Gene, Diagnosis, Genetic disease, Indication, Ethics, Legislation, Organ donation, Genetic counseling, Informed consent, Review, Human, Urinary system disease, Kidney disease, Benign neoplasm, Cyst, Genetics

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0048567

    Code Inist : 002B14E01. Création : 31/05/1999.