Occupational respiratory hypersensitivity caused by preparations containing acrylates in dental personnel.
Background Allergic contact dermatitis caused by acrylate compounds is common in dental personnel ; they also often complain of work-related respiratory or conjunctival symptoms.
Objective The aim of the present study was to report the cases of acrylates induced respiratory hypersensitivity in dental personnel diagnosed in Finland during the last 6 years.
Methods Occupational asthma, rhinitis, laryngitis and pharyngitis cases were diagnosed according to patient history, PEF monitoring, and a work-simulating provocation test.
Results Twelve cases of respiratory hypersensitivity caused by acrylates diagnosed in dental personnel (six dentists and six dental nurses) in 1992-97 are reported.
During this period one case of conjunctivitis and one of laryngitis have been published separately.
Nine cases of occupational asthma, two rhinitis cases, and one laryngitis case were verified according to the challenge tests with dental acrylate compounds (acrylates, methacrylates and epoxy acrylates).
Only three patients had positive skin-prick test reactions to common environmental allergens, and none reacted to acrylates in the skin-prick tests.
Five patients had an elevated total IgE (>110kU/L).
PEF follow-up showed an occupational effect in all examined eight patients with diagnosed asthma.
The mean duration of exposure to acrylates was 22 years, and the duration of respiratory symptoms 8 years. (...)
Mots-clés Pascal : Asthme, Allergie, Rhinite, Pharyngite, Laryngite, Acrylate copolymère, Méthacrylate copolymère, Exposition professionnelle, Dentisterie, Etiologie, Homme, Finlande, Europe, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Immunopathologie, ORL pathologie, Nez pathologie, Pharynx pathologie, Larynx pathologie, Médecine travail
Mots-clés Pascal anglais : Asthma, Allergy, Rhinitis, Pharyngitis, Laryngitis, Acrylate copolymer, Methacrylate copolymer, Occupational exposure, Dentistry, Etiology, Human, Finland, Europe, Respiratory disease, Obstructive pulmonary disease, Immunopathology, ENT disease, Nose disease, Pharynx disease, Larynx disease, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0046687
Code Inist : 002B06C02. Création : 31/05/1999.