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  1. Acanthamoeba keratitis : multicentre survey in England 1992-6.

    Article - En anglais

    Aim-To investigate the frequency, outcomes, and risk factors for acanthamoeba keratitis (AK) in England during the past 4 years.

    Methods-An ophthalmologist in 12 of the 14 regional health authorities (RHAs) coordinated identification of patients in their region presenting with AK between 1 October 1992 and 30 September 1996.

    Clinical and postal patient questionnaire data were analysed.


    243 patients (259 eyes) with an AK diagnosis were identified, equating to an annualised incidence of 0.14 per 100 000 individuals.

    UK resident patients for each year numbered 50,71,73, and 32 respectively.

    Among patients with sufficient data 170/237 (72%) were diagnosed early (within 30 days of presentation), 197/218 (90%) were treated with polyhexamethyl biguanide andlor chlorhexidine, and 401243 (16%) underwent surgery.

    Visual acuities of 6/12 or better were achieved by 222/259 (86%) eyes, including 84 eyes of patients under review or lost to follow up.

    Non-contact lens (CL) wearers were associated with delayed diagnosis, increased need for surgery and a poorer visual outcome (only 10118 eyes, 56%, achieved 6/12 acuity). 225/243 (93%) patients were CL wearers, and 205/243 (84%) were soft CL (SCL) users.

    Among SCL user respondents, previously identified risk factors-swimming with CL (47/138,34%), non-sterile CL rinsing (11/138,8%), omitted disinfection (85/138,62%), and chlorine release disinfection (65/138,47%) - were identified for 125/138 (91%) patients. (...)

    Mots-clés Pascal : Kératite, Infection, Cornée, Acanthamoeba, Lobosea, Protozoa, Parasitose, Angleterre, Grande Bretagne, Royaume Uni, Europe, Facteur risque, Pronostic, Homme, Oeil pathologie, Kératopathie

    Mots-clés Pascal anglais : Keratitis, Infection, Cornea, Acanthamoeba, Lobosea, Protozoa, Parasitosis, England, Great Britain, United Kingdom, Europe, Risk factor, Prognosis, Human, Eye disease, Keratopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0043785

    Code Inist : 002B05E02B1. Création : 31/05/1999.