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  1. Primary thrombophilia in Mexico : A prospective study.

    Article - En anglais

    A group of 102 Mexican Mestizo patients with appropriate clinical features suggestive of primary thrombophilia was prospectively studied.

    Thirty-nine percent of them had activated protein C resistance, but only four patients displayed the factor V Leiden mutation.

    Five percent of the individuals were found to be protein C deficient, whereas 2% had protein S deficiency.

    No cases of abnormalities in antithrombin III, plasminogen, tissue-type plasminogen activator or plasminogen activator inhibitor were found.

    The low prevalence of the activated protein C resistance genotype, probably stemming from the genetic admixture of the Mexican Mestizo group is noteworthy.

    Mots-clés Pascal : Hypercoagulabilité, Résistance, Protein C (activated), Serine endopeptidases, Peptidases, Hydrolases, Enzyme, Facteur V Leiden, Complication, Thrombose, Prévalence, Epidémiologie, Mexique, Amérique Centrale, Amérique, Prospective, Homme, Hémopathie, Coagulopathie, Maladie héréditaire, Appareil circulatoire pathologie, Vaisseau sanguin pathologie

    Mots-clés Pascal anglais : Hypercoagulability, Resistance, Protein C (activated), Serine endopeptidases, Peptidases, Hydrolases, Enzyme, Factor V Leiden, Complication, Thrombosis, Prevalence, Epidemiology, Mexico, Central America, America, Prospective, Human, Hemopathy, Coagulopathy, Genetic disease, Cardiovascular disease, Vascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0043578

    Code Inist : 002B19C. Création : 31/05/1999.