Objectives To determine the prevalence of Helicobacter pylori and risks for infection in a multi-ethnic inner city population, and to assess the effectiveness with which the infection can be eradicated in a relatively asymptomatic population of this type.
Design Analysis of results from a small research-based community programme of screening and eradication.
Tests were offered to matched groups of Asians and non-Asians from the general population.
Methods Those who attended for screening had a serological screening test for infection with H. pylori.
Data concerning possible risk factors for infection were collected by means of questionnaires.
Subjects testing positive were offered a prescription for eradication therapy (ranitidine bismuth citrate and clarithromycin) through their general practitioner, and success of eradication therapy was assessed by urea breath test.
Results The overall prevalence of infection in 155 subjects was found to be 51%. The difference between positive test rates in Asians (53%) and non-Asians (47%) was not significant (p=0.611).
In Asians, age and social class were risk factors for infection, but not gender or birth outside the UK.
Results were similar in those born in India and East Africa.
Of the 79 people who tested positive, 64 (81%) elected to take eradication therapy.
Compliance with medication was estimated to be 95% and successful eradication was achieved in 92% of cases. (...)
Mots-clés Pascal : Gastrite, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Dépistage, Traitement, Eradication, Facteur prédictif, Evaluation performance, Homme, Appareil digestif pathologie, Estomac pathologie
Mots-clés Pascal anglais : Gastritis, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Medical screening, Treatment, Eradication, Predictive factor, Performance evaluation, Human, Digestive diseases, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0038658
Code Inist : 002B05B02F. Création : 31/05/1999.