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  1. Optic neuritis with residual tunnel vision in perchloroethylene toxicity.

    Article - En anglais

    Case Report : In a 57-year-old female owner of a dry-cleaning shop, we describe the association of severe bilateral optic neuritis with unexpectedly high concentrations of perchloroethylene/metabolites in the blood and of chloroform in urine.

    Visual disturbances consisted of complete blindness for 9 days in the left eye, for 11 days in the right eye, with bright phosphenes and pain on eye rotation.

    Only central (2-3° radius) vision recovered in the following months.

    Conclusion :

    Although environmental concentrations of perchloroethylene were within normal limits, we measured five-fold increases in vapors emitted when ironing freshly dry-cleaned fabrics, and suggest that inhalation of perchloroethylene vapors was the cause of this case of ocular nerve toxicity, recapitulating a previous report of major perchloroethylene toxicity.

    Mots-clés Pascal : Ethylène(tétrachloro), Toxicité, Exposition professionnelle, Médecine travail, Homme, Névrite optique, Etude cas, Inhalation, Solvant organique, Nerf optique, Oeil pathologie, Système nerveux pathologie, Nerf crânien pathologie, Nettoyage à sec

    Mots-clés Pascal anglais : Ethylene(tetrachloro), Toxicity, Occupational exposure, Occupational medicine, Human, Optic nevritis, Case study, Inhalation, Organic solvent, Optic nerve, Eye disease, Nervous system diseases, Cranial nerve disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0037935

    Code Inist : 002B03L04. Création : 31/05/1999.