In a prospective survey of recent arthritis 96 patients had erosive and seropositive rheumatoid arthritis (RA).
Severe radiological changes in the hip joint (Larsen grade 3-5) were observed in 31 (32%) and acetabular protrusion in five (5%) patients 15 years after the onset of arthritis.
At the end offollow-up Larsen score 0 - 100 of peripheral joints (p<0.015), HAQ (p<0.001), ESR (p<0.001), and CRP (p<0.01) were significantly higher in patients with hip joint destruction than in those without.
Secondary amyloidosis was found in eight patients with and in three patients without hip involvement (p=0.002).
In survivorship analysis (the Larsen 0 - 2 grade hips) an overall predicted rate of survival was 80% after 14 years of rheumatoid arthritis.
When analyzed according to HLA-B27 the rate of radiological survival for the patients with a positive test was 62% and 87% for the others (p=0.02).
In conclusion, RA patients with high number of destructive peripheral joints (Larsen score) and high ESR or CRP should be carefully monitored due to the increased risk of hip destruction.
Mots-clés Pascal : Polyarthrite rhumatoïde, Symptomatologie, Facteur rhumatoïde, Arthrite, Hanche, Evolutivité, Epidémiologie, Pronostic, Etude longitudinale, Radiographie, Homme, Chronique, Destruction, Articulation, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune, Arthropathie, Radiodiagnostic
Mots-clés Pascal anglais : Rheumatoid arthritis, Symptomatology, Rheumatoid factor, Arthritis, Hip, Evolutivity, Epidemiology, Prognosis, Follow up study, Radiography, Human, Chronic, Destruction, Joint, Diseases of the osteoarticular system, Inflammatory joint disease, Immunopathology, Autoimmune disease, Arthropathy, Radiodiagnosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0034622
Code Inist : 002B15D. Création : 31/05/1999.