Accumulation of factors influencing children's middle ear disease : risk factor modelling on a large population cohort.
Study objectives-Data were analysed from a large national birth cohort to examine cumulative and interactive prediction from various risk factors for childhood middle ear disease, and to resolve conflicting evidence arising from small and incompletely controlled studies.
The large sample size permitted appropriate covariate adjustment to give generality, and permit demographic breakdown of the risk factors.
Setting-A large multi-purpose longitudinal birth cohort study of all births in the UK in one week in 1970, with multiple questionnaire sweeps.
Participants-Over 13 000 children were entered into the original cohort.
Data on over 12 000 children were available at the five year follow up.
Main outcome measures-For children at 5 years, parent reported data were available on health and social factors including data on two markers for middle ear disease : the occurrence of purulent (non-wax) ear discharge and suspected or confirmed hearing difficulty.
Main results-In those children who had ever had reported hearing difficulty (suspected or confirmed), after control for socioeconomic status, three of the classic factors (male sex, mother's smoking habits since birth, and attending day care) were significantly more frequent.
In those who had ever had ear discharge reported, only mother's smoking habit since birth was significantly more frequent.
However, it showed an orderly dose response relation. (...)
Mots-clés Pascal : Oreille moyenne pathologie, Epidémiologie, Facteur risque, Enfant, Homme, Etude cohorte, Royaume Uni, Europe, ORL pathologie
Mots-clés Pascal anglais : Middle ear disease, Epidemiology, Risk factor, Child, Human, Cohort study, United Kingdom, Europe, ENT disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0034334
Code Inist : 002B10D02. Création : 31/05/1999.