Disease control exerts evolutionary pressures that can lead to the evolution of resistance.
This has been seen in a spectacular fashion in the evolution of resistance to antibiotics, anti-virals and anti-parasitics.
Despite intense (and often successful) attempts to control infectious diseases through vaccination, there is still rather little evidence of the emergence of strains of pathogen resistant to vaccines.
This chapter asks why this should be so and what are the exceptions indicating that the evolution of vaccine resistance, though currently rare, is a possibility that should be planned for.
Mots-clés Pascal : Vaccination, Epidémiologie, Facteur prédictif, Infection, Contagion, Emergence, Résistance traitement, Physiopathologie, Réaction croisée, Homme, Immunoprophylaxie
Mots-clés Pascal anglais : Vaccination, Epidemiology, Predictive factor, Infection, Contagion, Emergence, Negative therapeutic reaction, Pathophysiology, Cross reaction, Human, Immunoprophylaxis
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0027027
Code Inist : 002B05A02. Création : 31/05/1999.