Complications of varicella in a defined central European population.
Aims-To describe complications of varicella requiring hospitalisation in a defined population (canton of Bern) and to compare the hospitalisation rates for varicella with published data.
Methods-Retrospective analysis of hospital records of patients less than 16 years of age admitted with complications of varicella to the hospitals serving this population (University Children's Hospital of Bern and the Wildermeth Children's Hospital of Biel, Switzerland), and calculation of hospitalisation rates for varicella and its complications based on birth rates and varicella antibody prevalence rates.
From 1986 to 1996,113 cases (median age, 5.6 years) were identified.
Younger siblings were overrepresented (odds ratio (OR), 1.42 ; 95% confidence interval (CI), 1.09 to 1.84).
Central nervous system (CNS) complications (26 patients ; 23%) were found predominantly in previously healthy children (relative risk, 7.1 ; 95% CI, 1.01 to 49.86).
Group A bêta haemolytic streptococci were recovered from only one of 35 patients with bacterial complications.
The hospitalisation rates for primary varicella (9.2/104 cases ; 95% CI, 7.4 to 11/104), skin infections (2.0/104 cases ; 95% CI, 1.2 to 2.9/104), and pneumonia (0.8/104 cases ; 95% CI, 0.3 to 1.3/104) were significantly lower than reported previously.
The CNS complication rate (2.2/104 cases ; 95% CI, 1.3 to 3.1/104) was among the highest rates reported. (...)
Mots-clés Pascal : Varicelle, Virose, Infection, Complication, Hospitalisation, Etude statistique, Etude comparative, Suisse, Europe, Incidence, Prévention, Vaccination, Indication, Enfant, Homme, Virologie, Epidémiologie
Mots-clés Pascal anglais : Varicella, Viral disease, Infection, Complication, Hospitalization, Statistical study, Comparative study, Switzerland, Europe, Incidence, Prevention, Vaccination, Indication, Child, Human, Virology, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0025774
Code Inist : 002B05C02B. Création : 31/05/1999.