The relationship between diet and pancreatic cancer remains unclear.
In this study, we assessed the role of diet and nutrition as risk factors for pancreatic cancer, using data obtained from direct interviews only, rather than data from less reliable interviews with next of kin.
We evaluated whether dietary factors could explain the higher incidence of pancreatic cancer experienced by black Americans compared with white Americans.
We conducted a population-based case-control study of pancreatic cancer diagnosed in Atlanta (GA), Detroit (MI), and 10 New Jersey counties from August 1986 through April 1989.
Reliable dietary histories were obtained for 436 patients and 2003 general-population control subjects aged 30-79 years.
Obesity was associated with a statistically significant 50% - 60% increased risk of pancreatic cancer that was consistent by sex and race.
Although the magnitude of risk associated with obesity was identical in blacks and whites, a higher percentage of blacks were obese than were whites (women : 38% versus 16% ; men : 27% versus 22%). A statistically significant positive trend in risk was observed with increasing caloric intake, with subjects in the highest quartile of caloric intake experiencing a 70% higher risk than those in the lowest quartile. (...)
Mots-clés Pascal : Tumeur maligne, Pancréas, Obésité, Facteur risque, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Etude cas témoin, Homme, Etat nutritionnel, Appareil digestif pathologie, Pancréas pathologie, Trouble nutrition
Mots-clés Pascal anglais : Malignant tumor, Pancreas, Obesity, Risk factor, Epidemiology, United States, North America, America, Case control study, Human, Nutritional status, Digestive diseases, Pancreatic disease, Nutrition disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0023218
Code Inist : 002B13C01. Création : 31/05/1999.