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  1. Evaluation of the risk for metachronous colorectal neoplasms following intestinal polypectomy : A clinical, endoscopic and pathological study.

    Article - En anglais

    BACKGROUND/AIMS 

    Surveillance programs are recommended for patients with previous intestinal polypectomy because of the high rate of adenomatous recurrences and risk of subsequent colorectal cancer.

    The parameters to identify patients at higher risk and the length and schedules of follow-up have not yet been established.

    We considered some clinical, endoscopic and pathological parameters in order to assess the probability of developing new colorectal neoplasms and eventually to schedule proper surveillance programs.

    METHODOLOGY 

    Patients with removed adenomas were enrolled into a clinico-endoscopic follow-up, comprehensive of two colonoscopies the first at 1 year and the second at 3 years.

    We evaluated the risk of new neoplasms dividing the patients into four groups according to the number and size of the adenomas removed and the parameters considered.

    RESULTS 

    Of 164 patients enrolled 156 completed the study.

    We had an overall 21.3% of adenomatous recurrences at 1 year and 12.8% at 3 years.

    Most of the adenomas removed were tubular and small in size (<1 cm).

    The percentage of patients who had adenomas with advanced pathological features was 1.82% at 1 year and 0.64% at 3 years.

    The increase in number and size of the adenomas removed on the initial colonoscopic examination was the only one parameter statistically significant, X21 (trend) 5.11 ; p<0.05 at the first follow-up and X21 (trend) 4.87 ; p<0.05 at the second follow-up. (...)

    Mots-clés Pascal : Polype, Intestin, Traitement, Résection chirurgicale, Incidence, Synchrone, Carcinome, Côlon, Rectum, Epidémiologie, Homme, Appareil digestif pathologie, Intestin pathologie, Tumeur bénigne, Chirurgie, Tumeur maligne, Côlon pathologie, Rectum pathologie

    Mots-clés Pascal anglais : Polyp, Gut, Treatment, Surgical resection, Incidence, Synchronous, Carcinoma, Colon, Rectum, Epidemiology, Human, Digestive diseases, Intestinal disease, Benign neoplasm, Surgery, Malignant tumor, Colonic disease, Rectal disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0016693

    Code Inist : 002B13B01. Création : 31/05/1999.