logo BDSP

Base documentaire


  1. Cholesterolemia in colorectal cancer.

    Article - En anglais

    BACKGROUND/AIMS 

    Colorectal cancer incidence is higher in developed countries.

    High fat intake is one of the risk factors.

    However, many studies observed lower cholesterol serum levels on diagnosis of colorectal cancer.

    The aim of this assay was to study the serum cholesterol levels in patients with colorectal cancer and compare these values with individuals of the same age and sex.

    METHODOLOGY 

    Cholesterol serum levels of 85 patients with colorecectal cancer were determined.

    Each of the patients with colorectal cancer were matched with an individual without cancer of the same age and sex.

    Total cholesterol concentrations were determined using an enzymatic colorimetric method.

    RESULTS 

    The mean serum of cholesterol was 183,4 for the colorectal group and 209.7 for the control group.

    This difference was statistically significant.

    This difference was more evident in patients with colon cancer and older than 60 years of age.

    There was no difference between the different Dukes'stage.

    CONCLUSIONS 

    Our study suggest an association between low blood cholesterol and colorectal cancer.

    We believe that the lower level of cholesterol observed in these patients is a consequence between the difference of colorectal carcinogenesis.

    Mots-clés Pascal : Carcinome, Côlon, Rectum, Facteur risque, Régime alimentaire enrichi, Graisse, Taux concentration, Cholestérol, Etude comparative, Homme, Tumeur maligne, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie, Nutrition

    Mots-clés Pascal anglais : Carcinoma, Colon, Rectum, Risk factor, Supplemented diet, Grease, Concentration factor, Cholesterol, Comparative study, Human, Malignant tumor, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease, Nutrition

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0016680

    Code Inist : 002B13B01. Création : 31/05/1999.