Background Uncertainty surrounds the best approach to management of patients with symptomless abdominal aortic aneurysms of 4.0-5.5 cm in diameter.
The UK Small Aneurysm Trial showed that surveillance and early prophylactic elective surgical repair had similar survival benefits.
We compared the impact on health service costs and quality of life of these two management strategies.
Methods We measured and valued direct health service costs for use of National Health Service resources.
We used the Medical Outcomes Study short-form patients'health survey to measure health-related quality of life in several areas of functional status and well-being.
We did analyses by intention to treat for all 1090 patients in the 93 trial centres.
Findings The mean cost of treatment in the early-surgery group was significantly higher than that for ultrasonographic surveillance (UK£4978 vs 3914, difference £1064 [95% Cl 799-1328]). This finding was robust for a range of assumptions that varied the time between surveillance visits and the mean unit cost of elective aneurysm repair.
Health-related quality of life was generally similar 12 months after randomisation for the two groups, but early-surgery patients reported positive improvement in current health perceptions and less negative change in bodily pain.
Interpretation Cost was higher for early surgery than for ultrasonographic surveillance for small aortic aneurysms. (...)
Mots-clés Pascal : Anévrysme, Aorte abdominale, Petite dimension, Chirurgie, Précoce, Analyse coût, Imagerie ultrasonore, Surveillance, Evaluation, Qualité vie, Homme, Etude comparative, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Radiodiagnostic, Imagerie médicale, Economie santé
Mots-clés Pascal anglais : Aneurysm, Abdominal aorta, Small dimension, Surgery, Early, Cost analysis, Ultrasound imaging, Surveillance, Evaluation, Quality of life, Human, Comparative study, Cardiovascular disease, Vascular disease, Radiodiagnosis, Medical imagery, Health economy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0012366
Code Inist : 002B25F. Création : 31/05/1999.