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  1. The longterm outcomes of rheumatoid arthritis : Work disability : A prospective 18 year study of 823 patients.

    Article - En anglais


    Work disability is a common outcome of rheumatoid arthritis (RA).

    Yet there have been no longitudinal, longterm, prospective studies of work disability in this illness.

    This 18 year longitudinal study investigates the rate of work disability, its concomitants, and its predictors. using a large series of clinical, laboratory, and self-report measures.


    In 1974, a computerized database was developed for the contemporaneous entry of all patient visits.

    Data included clinical, laboratory, and self-report information.

    Patients were also assessed by mailed questionnaires at 6 month intervals.

    In 1994, patients with RA were interviewed in detail about lifetime work status and work disability.


    Work disability was estimated to occur in 25% at 6.4 years and 50% at 20.9 years after disease onset, and most disability occurred late in the course of disease.

    Work disability was predicted by almost every demographic and clinical variable.

    Education level, body mass index (BMI), erythrocyte sedimentation rate, rheumatoid factor, pain.

    Health Assessment Questionnaire (HAQ) disability, and physical demands of the job were independently associated with disability.

    Over the course of their illness, the work disabled had a 35% reduction in family income, and had more abnormal scores for joint counts, grip strength, sedimentation rate, pain, global severity, HAQ disability, and anxiety and depression. (...)

    Mots-clés Pascal : Polyarthrite rhumatoïde, Incapacité, Poste travail, Epidémiologie, Symptomatologie, Long terme, Pronostic, Etude longitudinale, Questionnaire, Homme, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune

    Mots-clés Pascal anglais : Rheumatoid arthritis, Disability, Workplace layout, Epidemiology, Symptomatology, Long term, Prognosis, Follow up study, Questionnaire, Human, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Immunopathology, Autoimmune disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0008660

    Code Inist : 002B15D. Création : 31/05/1999.