Among some 7500 respondents with known place of birth who had completed a nationwide questionnaire survey for multiple sclerosis (MS) in France in 1986, there were 26 () born in former French North Africa (Algeria.
They had migrated to France between 1923 and 1986. but 66% came between 1956 and 1964.
Two-thirds were from Algeria, where virtually the entire European population had emigrated in 1962 at the end of the Algerian war for independence.
The migrants were younger at prevalence day (mean 43.4 years) and at onset (29.4 years) than the French-born MS (46.6 : 31.3 years).
Eight migrants lacked age information.
The 225 migrants with onset more than 1 year after immigration presumably acquired their MS in France.
They provided an age adjusted (US 1960) MS prevalence rate 1.54 times that for all France.
If the latter is taken at 50 per 100.000 population their estimated adjusted rate is 76.8 with 95% confidence interval of 67.1 to 87.5. The other 27 with presumed acquisition in North Africa gave an estimated adjusted prevalence of 16.6 per 100,000 (95% CI 10.9-24.1).
For those migrants with acquisition in France there was a mean interval of 13 years between immigration or age 11 and clinical onset, with a minimum of 3 years. (...)
Mots-clés Pascal : Sclérose en plaque, Migration population, Afrique du Nord, Afrique, France, Europe, Age apparition, Facteur risque, Epidémiologie, Prévalence, Facteur milieu, Homme, Système nerveux pathologie, Système nerveux central pathologie, Maladie inflammatoire
Mots-clés Pascal anglais : Multiple sclerosis, Population migration, North Africa, Africa, France, Europe, Age of onset, Risk factor, Epidemiology, Prevalence, Environmental factor, Human, Nervous system diseases, Central nervous system disease, Inflammatory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0004978
Code Inist : 002B17F. Création : 31/05/1999.