Conference "The Determination, Treatment, and Prevention of Obesity". Sunset Beach, NC, USA, 1997/10/23.
The question of whether the range of recommended body weights should remain the same throughout adulthood or should be more liberal (higher) in older adults has been extremely controversial.
Much of the debate has centered on methodologic issues including sources of confounding and the precision of risk estimates.
These methodologic issues are reviewed, and studies that compare the body mass index (BMI) - mortality relationship within appropriate age strata are summarized.
Several studies have attempted to control for major confounders, but were too small in size to produce comparisons across age groups.
Only three studies had as many as 400 deaths in each age group, and only one of those attempted to control for confounding variables.
This study, a recent analysis of the Cancer Prevention Study-I, combined attention to possible confounding variables with the statistical power that comes from a large sample.
The analysis indicated that the optimum 12-year survival was associated with a lean BMI (19-21.9) between the ages of 30 and 74 years.
After 74 years, the optimum BMI was considerably higher.
This study had several limitations and its generalizability is restricted, but nevertheless, it offers the best evidence to date on the impact of age on the BMI-mortality association. (...)
Mots-clés Pascal : Epidémiologie, Age, Poids corporel, Optimum, Indice masse corporelle, Mortalité, Obésité, Etat nutritionnel, Trouble nutrition, Article synthèse, Homme
Mots-clés Pascal anglais : Epidemiology, Age, Body weight, Optimum, Body mass index, Mortality, Obesity, Nutritional status, Nutrition disorder, Review, Human
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Cote : 99-0003438
Code Inist : 002B30A01A2. Création : 31/05/1999.