Defining obesity : An adventure in cardiovascular disease epidemiology.
Conference "The Determination, Treatment, and Prevention of Obesity". Sunset Beach, NC, USA, 1997/10/23.
While the association of overweight and health, as well as longevity, has been scrutinized in volumes of research, the association of overweight with cardiovascular disease is a dominant theme in the medical literature.
This report will detail the arguments and present selected summaries of published reports that support the emerging consensus that overweight and obesity have the major causal role in the ongoing epidemic of cardiovascular disease in the United States.
Examples will include relative risk and attributable risk estimates for several metabolic perturbations caused by overweight, including type 2 diabetes mellitus and hypertension.
Results of the Nurses Health Study, which found a fivefold increased risk of type 2 diabetes among women with body mass index between 24.0 and 24.9 compared to the referent group with body mass index <=22, will be highlighted.
The presentation will also explicitly identify the position of excess adiposity in the causal chain that leads from overnutrition to the majority of cardiovascular disease, Based on the position in the causal sequence, a strategy for defining the threshold of overweight'will be described.
From the foregoing, it is concluded that the overweight threshold should be no higher than body mass index=25. (...)
Mots-clés Pascal : Epidémiologie, Surcharge pondérale, Seuil, Indice masse corporelle, Distribution, Tissu adipeux, Obésité, Définition, Appareil circulatoire pathologie, Etiologie, Etat nutritionnel, Trouble nutrition, Article synthèse, Homme
Mots-clés Pascal anglais : Epidemiology, Overweight, Threshold, Body mass index, Distribution, Adipose tissue, Obesity, Definition, Cardiovascular disease, Etiology, Nutritional status, Nutrition disorder, Review, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0003437
Code Inist : 002B22B. Création : 31/05/1999.