Objective To examine the relation between nut consumption and risk of coronary heart disease in a cohort of women from the Nurses'Health Study, Design Prospective cohort study.
Setting Nurses'Health Study.
Subjects 86 016 women from 34 to 59 years of age withou previously diagnosed coronary heart disease, stroke, or cancer at baseline in 1980.
Main outcome measures Major coronary heart disease including non-fatal myocardial infarction and fatal coronary heart disease.
Results 1255 major coronary disease events (861 1 cases of non-fatal myocardial infarction and 394 cases of fatal coronary heart disease) occurred during 14 years of follow up ter adjusting for age, smoking, and other known risk factors for coronary heart disease omen who ate more than five units of nuts (one unit equivalent to I oz of nuts) a week (frequent consumption) had a significantly lower risk of total coronary heart disease (relative risk 0.65,95% confidence interval 0.47 to 0.89, P for trend=0.0009) than women who never ate nuts or who ate less than one unit a month (rare consumption).
The magnitude of risk reduction was similar for both fatal coronary heart disease (0.6 1,0.35 to 1.05, P for trend=0.007) and non-fatal myocardial infarction (0.68,0.47 to 1.00, P for trend=0.04).
Further adjustment for intakes of dietary fats, fibre, vegetables, and fruits did not alter these results. (...)
Mots-clés Pascal : Cacahuète, Noisette, Régime alimentaire, Cardiopathie coronaire, Epidémiologie, Facteur risque, Prévention, Homme, Femelle, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Peanut, Hazelnut, Diet, Coronary heart disease, Epidemiology, Risk factor, Prevention, Human, Female, United States, North America, America, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0001801
Code Inist : 002B12A03. Création : 31/05/1999.