We evaluated the risk of gastric cardia cancer by occupation and industry in a case-control study using information from death certificates for 24 US states in 1984-1992.
One thousand fifty-six cases of gastric cardia cancer were identified among men aged 20 years or more, including 1,023 whites and 33 blacks.
Controls were 5,280 subjects who died of nonmalignant diseases, 5 : 1 matched to cases by geographic region, race, gender, and 5-year age group.
Among white men, occupations with elevated risk included financial managers (odds ratio [OR]=6.1 ; 95% confidence interval [CI], 1.3-28.8), janitors and cleaners (OR=1.7 ; 95% CI, 1.0-2.9), production inspectors (OR=3.2 ; 95% CI, 1.5-6.9), and truck drivers (OR=1.5 ; 95% CI, 1.0-2.2).
Industries with elevated risk included pulp and paper mills (OR=2.0 ; 95% CI, 1.0-37), newspaper publishing and printing (OR=2.6 ; 95% CI, 1.0-6.3), industrial and miscellaneous chemicals (OR=2.0 ; 95% CI, 1.0-3.9), water supply and irrigation (OR=5.6 ; 95% CI, 1.6-19.9).
Among black men, risks were nonsignificantly increased for subjects employed in railroads (3 cases, 2 controls) and for carpenters (3 cases, 0 controls).
We created job-exposure matrices for asbestos, inorganic dust, metal dust, lead, polycyclic aromatic hydrocarbons, nitrogen oxides, nitrosamines, sulfuric acid, fertilizers, herbicides, other pesticides, and wood dust. (...)
Mots-clés Pascal : Exposition professionnelle, Médecine travail, Toxique, Industrie, Toxicité, Tumeur maligne, Estomac, Facteur risque, Comparaison interindividuelle, Profession, Etude cas témoin, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Certificat décès, Recherche rétrospective, Analyse statistique, Homme, Appareil digestif pathologie, Estomac pathologie
Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Poison, Industry, Toxicity, Malignant tumor, Stomach, Risk factor, Interindividual comparison, Profession, Case control study, United States, North America, America, Epidemiology, Death certificate, Retrospective searching, Statistical analysis, Human, Digestive diseases, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0001575
Code Inist : 002B13B01. Création : 31/05/1999.