Objectives-To estimate the risk of cancer and death in Swedish insulation workers some years after their exposure to asbestos had stopped.
One hypothesis was that the risk of lung cancer would tend to decrease some years after the exposure had ended.
Methods-In a cohort study the cancer morbidity and cause of death was investigated in 248 insulation workers and compared with the corresponding morbidity and mortality in the general population.
Due to stringent regulations, exposure to asbestos of all types had almost ended in Sweden in the mid-1970s.
Through a questionnaire, surviving insulation workers were asked about their exposure to asbestos and their smoking habits.
Between 1970 and 1994 there were 86 deaths compared with the 46.0 expected (standardised incidence ratio (SIR) 1.9 ; 95% confidence interval (95% CI) 1.5 to 2.3), the increase was mainly due to an increased cancer mortality.
The morbidity was increased for lung cancer (11 cases upsilon 2.5 expected (SIR 4.4 ; 95% CI 2.2 to 7.9)), peritoneal mesothelioma (seven cases ; no expected incidence could be calculated as the occurrence is too rare in the general population), cancer in pancreas (five cases upsilon 0.7 expected (SIR 7.1 ; 95% CI 2.3 to 16.7)). No cases of pleural mesothelioma were found.
The risk of lung cancer did not tend to approach that of the general population after the exposure to asbestos decreased. (...)
Mots-clés Pascal : Amiante, Exposition professionnelle, Médecine travail, Isolation, Industrie construction, Mésothéliome malin, Plèvre, Homme, Morbidité, Mortalité, Epidémiologie, Suède, Europe, Facteur risque, Toxicité, Etude longitudinale, Péritoine, Incidence, Appareil respiratoire pathologie, Plèvre pathologie, Tumeur maligne
Mots-clés Pascal anglais : Asbestos, Occupational exposure, Occupational medicine, Insulation, Construction industry, Malignant mesothelioma, Pleura, Human, Morbidity, Mortality, Epidemiology, Sweden, Europe, Risk factor, Toxicity, Follow up study, Peritoneum, Incidence, Respiratory disease, Pleural disease, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0001519
Code Inist : 002B11A. Création : 31/05/1999.