Objectives-To study the role of individual and occupational risk factors for asthma in furniture workers.
Methods-296 workers were examined (258 men, 38 women) with a questionnaire of respiratory symptoms and diseases, baseline spirometry, bronchial provocative test with methacholine, and skin prick tests.
Non-specific bronchial hyperreactivity was defined as when a provocative dose with a fall of 20% in forced expiratory volume in 1 second (PD20FEV1) was<0.8 mg and atopy in the presence of at least one positive response to skin prick tests.
Workers were subdivided into spray painters (exposed to low concentrations of diisocyanates and solvents), woodworkers (exposed to wood dusts), and assemblers (control group).
The prevalences of attacks of shortness of breath with wheezing and dyspnoea were higher in spray painters (13.5% and 11.5% respectively) than in woodworkers (7.7% and 6.3%) or in assemblers (1.6% and 1.6%) ; prevalences of chronic cough, asthma, and rhinitis were also slightly but not significantly higher in spray painters and in woodworkers than in assemblers.
The difference in the prevalence of respiratory symptoms among the job titles was due to the atopic subjects, who showed a higher prevalence of chronic cough, wheeze, shortness of breath with wheeze, dyspnoea, and asthma in spray painters than in the other groups.
The prevalence of non-specific bronchial hyperreactivity in subjects who performed bronchial provocative tests was 17. (...)
Mots-clés Pascal : Pollution intérieur, Diisocyanate organique, Fibre bois, Exposition professionnelle, Inhalation, Solvant organique, Médecine travail, Asthme, Toxicité, Atopie, Mobilier, Fabrication, Homme, Surveillance biologique, Prévalence, Analyse statistique, Facteur risque, Comparaison interindividuelle, Age, Profession, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Immunopathologie, Allergie
Mots-clés Pascal anglais : Indoor pollution, Organic diisocyanate, Wood fiber, Occupational exposure, Inhalation, Organic solvent, Occupational medicine, Asthma, Toxicity, Atopy, Furniture, Manufacturing, Human, Biological monitoring, Prevalence, Statistical analysis, Risk factor, Interindividual comparison, Age, Profession, Respiratory disease, Obstructive pulmonary disease, Immunopathology, Allergy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0001378
Code Inist : 002B11D. Création : 31/05/1999.