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  1. Fulltext. Epidemiology of the non-Hodgkin's lymphomas : Distributions of the major subtypes differ by geographic locations.

    Article - En anglais



    There has been no previous systematic study of the distribution of the major subtypes of non-Hodgkin's lymphoma (NHL) across geographic regions. although there have been isolated reports of such differences.


    As part of a a clinical evaluation of the International Lymphoma Study Group (ILSG) classification of NHL. we classified 1378 NHLs from eight different geographic sites (Omaha.

    NE. USA : Vancouver.

    BC. Canada ; Capetown.

    South Africa ; London.

    England ; Würzburg/Göttingen, Germany ; Lyon.

    France ; Locarno/Bellinzona, Switzerland ; and Hong Kong) using the ILSG classification.


    Substantial differences were found in the distribution of the major subtypes of NHL across geographic regions (P<0.0001).

    A greater percentage of follicular lymphoma was seen in North America.

    London and Capetown (31% versus 14% at other sites).

    Peripheral T-cell lymphoma was more common in London, Capetown and Hong Kong (9%) than elsewhere (3%). In Locarno/Bellinzona. higher percentages of mediastinal large B-cell lymphoma (9% versus 2% elsewhere) and mantle cell lymphoma (14% versus 6% elsewhere) were seen.

    Angiocentric nasal T-/NK-cell lymphoma was only seen in Hong Kong (8%) and Lyon (2%). Conclusions.

    Our study provides evidence that the distribution of NHL subtypes differs by geographic region. (...)

    Mots-clés Pascal : Lymphome non hodgkinien, Epidémiologie, Type histologique, Soustype, Répartition géographique, Homme, Hémopathie maligne, Lymphoprolifératif syndrome

    Mots-clés Pascal anglais : Non Hodgkin lymphoma, Epidemiology, Histological type, Subtype, Geographic distribution, Human, Malignant hemopathy, Lymphoproliferative syndrome

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0001132

    Code Inist : 002B19B. Création : 31/05/1999.