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  1. Systematic reviews and meta-analysis : a structured review of the methodological literature.

    Article - En anglais


    To systematically review methods for systematic review/meta-analysis in order to identify the different methodological and statistical methods that have been proposed.

    A summary of the main findings is presented here, with emphasis given to health services research topics.


    A thorough systematic search for methodological papers was carried out using a variety of methods, including the use of electronic databases.

    Approximately 1000 potentially relevant references were identified, a number of them from education, psychology and sociology.


    After briefly reviewing the procedural methods required to carry out a review, and the basic statistical methods used to combine study estimates, less established methods are discussed.

    These include methods for dealing with publication bias, meta-regression, meta-analysis of individual patient data, the synthesis of non-randomized evidence alone and in combination with randomized studies, Bayesian modelling and economic evaluation through meta-analysis.

    Recommendations for meta-analytical practice are given ; these are either distilled from previous guidelines, or constructed where there appears to be a broad consensus across the literature. (...)

    Mots-clés Pascal : Statistique, Méthodologie, Bibliographie, Documentation

    Mots-clés Pascal anglais : Statistics, Methodology, Bibliography, Documentation

    Logo du centre Notice produite par :
    Observatoire Régional de la Santé Auvergne-Rhône-Alpes

    Code Inist : 002B30A11. Création : 31/05/1999.