Environmental factors facilitating allergic sensitization and atopic manifestation in early childhood.
Ten Years of Food Allergy Prevention with Partial Whey Hydrolysate H.A. Formula. Symposium. Munchen, DEU, 1997/06/11.
Of the 7609 infants in the German Multicenter Atopy Study, 1314 were studied prospectively.
Among these, 499 infants (38%) were considered at high risk with two or more atopic first degree family members and/or a cord blood IgE value above 0.9 kU/I. The incidence of recurrent wheezing and atopic dermatitis was high during the first three months of life.
Wheezing in infants less than two years of age was often associated with high specific serum antibody level for respiratory syncytial virus.
IgE antibodies to dust mite and cat were observed in 1.1 - 5.5% and 2.5-5.3% of samples during the first 3 years of life.
At the age of three years, children who had been exposed tobacco before or after birth had a higher prevalence of sensitization to foods.
The aim of primary allergy prevention studies should be to reduce exposure to indoor allergens and tobacco smoke.
Mots-clés Pascal : Epidémiologie, Facteur risque, Sensibilisation, Allergène, Virus syncytial humain, Spumavirinae, Retroviridae, Virus, Poussière maison, Chat, Fissipedia, Carnivora, Mammalia, Vertebrata, Dermatite atopique, Asthme, Tabac, IgE, Allergie, Atopie, Immunopathologie, Peau pathologie, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Nourrisson, Homme, Allemagne, Europe
Mots-clés Pascal anglais : Epidemiology, Risk factor, Sensitization, Allergen, Human syncytial virus, Spumavirinae, Retroviridae, Virus, House dust, Cat, Fissipedia, Carnivora, Mammalia, Vertebrata, Atopic dermatitis, Asthma, Tobacco, IgE, Allergy, Atopy, Immunopathology, Skin disease, Respiratory disease, Obstructive pulmonary disease, Infant, Human, Germany, Europe
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0537905
Code Inist : 002B30A01C. Création : 23/03/1999.