The aim of this study was to evaluate the outcome and late sequelae of patients with esophageal atresia or tracheoesophageal fistula.
Sixty patients with esophageal atresia or tracheoesophageal fistula (EA-TEF) were treated in Tampere University Hospital in the years 1963 through 1993.
Long-term outcome was evaluated with a questionnaire, pulmonary and esophageal function test results, 24-hour pH level monitoring, tracheobronchoscopy findings, and esophagogastroscopy with biopsy sections and samples for bacterial cultures.
One third of the respondents reported having impaired quality of life because of respiratory infections, dyspnea, and difficulties in swallowing and coughing at night.
Eighteen percent had gastroesophageal reflux (GER) symptoms.
The rate of symptoms decreased with age.
Impaired pulmonary function, GER, abnormal esophageal peristalsis, and transit time were registered.
Tracheobronchoscopy showed tracheal narrowing and inflammation in one third ; in histopathologic analysis, however, the rate of inflammation was more than doubled.
Histologically, esophageal inflammation was found in 51%, Barrett's esophagus in 6%, and a Helicobacter pylori infection in 21% of cases.
The severity of GER, esophageal peristaltic abnormality, tracheal inflammation, and impairment of pulmonary function seems to be alleviated with age. (...)
Mots-clés Pascal : Atrésie, Oesophage, Traitement, Fistule, Oesotrachéal, Chirurgie, Séquelle, Long terme, Finlande, Europe, Etude statistique, Fonction respiratoire, Reflux gastrooesophagien, Dysphagie, Enfant, Homme, Adulte, Maladie congénitale, Appareil respiratoire pathologie, Trachée pathologie, Appareil digestif pathologie, Oesophage pathologie
Mots-clés Pascal anglais : Atresia, Esophagus, Treatment, Fistula, Tracheoesophageal, Surgery, Sequela, Long term, Finland, Europe, Statistical study, Lung function, Gastroesophageal reflux, Dysphagia, Child, Human, Adult, Congenital disease, Respiratory disease, Diseases of the trachea, Digestive diseases, Esophageal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0535519
Code Inist : 002B25G01. Création : 23/03/1999.