We prospectively compared the impact on quality of life and cost effectiveness between ablation and medication as an initial strategy for patients with paroxysmal supraventricular tachycardia (SVT).
Seventy-nine consecutive patients with newly documented paroxysmal SVT were treated with either ablation or medication.
Health surveys (SF-36 and disease-specific questions) were obtained at baseline and after 12 months of follow up.
Cost of health care utilization for the 6 months before and after treatment were measured.
Both medication and ablation improved quality of life.
However, ablation improved quality of life in more general health categories than medication.
At follow up, ablation was associated with significantly improved quality of life in the bodily pain (63 ± 24 vs 81 ± 20, p<0.005), general heal (69 ± 21 vs 79 ± 21, p<0.05), vitality (55 ± 21 vs 66 ± 22, p<0.05), and role emotion (78 ± 36 vs 94 ± 17, p<0.05) categories when compared with medication.
Although both medication and ablation decreased frequency of disease-specific symptoms, ablation resulted in complete amelioration of symptoms in more patients (33% vs 74%). Potential long-term costs were similar for medication and ablation.
In conclusion, ablation improves health-related quality of life to a greater extent, and in more aspects of general and disease-specific health than medication.
Mots-clés Pascal : Tachycardie paroxystique supraventriculaire, Ablation, Faisceau accessoire, Radiofréquence, Antiarythmique, Analyse coût, Economie santé, Qualité vie, Chimiothérapie, Traitement, Efficacité traitement, Homme, Etude comparative, Appareil circulatoire pathologie, Cardiopathie, Trouble rythme cardiaque, Trouble excitabilité, Traitement instrumental
Mots-clés Pascal anglais : Paroxysmal supraventricular tachycardia, Ablation, Accessory bundle, Radiofrequency, Antiarrhythmic agent, Cost analysis, Health economy, Quality of life, Chemotherapy, Treatment, Treatment efficiency, Human, Comparative study, Cardiovascular disease, Heart disease, Arrhythmia, Excitability disorder, Instrumentation therapy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0534036
Code Inist : 002B12A02. Création : 23/03/1999.