Using the European Community (EC) criteria for classification Vitali et al.
Arthritis Rheum 1993 ; 36 : 340-7, we report the prevalence estimates of Sjögren's syndrome (SS) from a general population and present the first population data to assess the impact of the syndrome.
A cross-sectional population-based survey performed on 1000 adults, aged 18-75 yr, randomly selected from a population register.
Responders to the initial postal phase were invited for an interview.
The five criteria measured at interview were :
(1) the reporting of subjective oral symptoms lasting for>3 months ;
(2) the reporting of subjective ocular symptoms lasting for>3 months ;
(3) Schirmer-I test ;
(4) unstimulated salivary flow ;
(5) autoantibodies [Ro (SS-A),
La (SS-B), rheumatoid factor (RF), antinuclear antibodies (ANA) ]. SS was diagnosed if at least four of these five criteria were positive.
The MOS Short-form 36 (SF-36), General Health Questionnaire (GHQ) and the Health and Fatigue Questionnaire (HFQ) were completed by subjects after the interview, and scores were compared between those with and without a diagnosis of SS.
A total of 341 subjects completed both the postal questionnaire and home visit.
A diagnosis of SS could be given to 13 subjects.
After adjusting for the presence of possible bias due to non-response, our best estimate of the prevalence of SS in the study population was 33 per 1000 subjects (95% CI 22-44). (...)
Mots-clés Pascal : Sjogren syndrome, Adulte, Homme, Symptomatologie, Epidémiologie, Prévalence, Etude transversale, Vieillard, Coping, Psychométrie, Questionnaire, Oeil pathologie, Stomatologie, Maladie système, Immunopathologie, Maladie autoimmune
Mots-clés Pascal anglais : Sjogren syndrome, Adult, Human, Symptomatology, Epidemiology, Prevalence, Cross sectional study, Elderly, Coping, Psychometrics, Questionnaire, Eye disease, Stomatology, Systemic disease, Immunopathology, Autoimmune disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0530935
Code Inist : 002B07. Création : 23/03/1999.