In this study, the various clinicoepidemiological characteristics and long-term follow-up of patients operated on for ulcerative colitis in Greece over a period of 15 years, are reviewed.
A total number of 69 out of 413 patients with ulcerative colitis (17.8%) seen and followed-up for a mean period of 12 years, had undergone ileorectal anastomosis (45.6%), total proctocolectomy with permanent ileostomy (35.6%), ileal-anal pouch anastomosis (17.6%) and Kock ileostomy (1.5%), mainly for bad response to conservative treatment (78.3%). Other causes for operation were large bowel cancer (8.7%), profound hemorrhage (4.3%), toxic megacolon (1.4%), and rectovaginal fistula (1.4%). Almost half of the operations (45%) were performed between the first and fourth year after the establishment of diagnosis.
A number of statistically highly significant differences between the operated and non-operated group of patients were noticed.
So, patients operated on had more extensive disease in comparison with non-operated ones and were younger at the time of diagnosis.
The overall perioperative morbidity and mortality were 6% and 5% respectively.
Survival was not statistically significantly different between operated and non-operated patients and also did not differ significantly between men and women.
Most of the deaths in the operated and non-operated group of patients were unrelated to ulcerative colitis. (...)
Mots-clés Pascal : Rectocolite ulcérohémorragique, Traitement, Résection chirurgicale, Indication, Technique, Evolution, Complication, Epidémiologie, Homme, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire, Chirurgie
Mots-clés Pascal anglais : Ulcerative colitis, Treatment, Surgical resection, Indication, Technique, Evolution, Complication, Epidemiology, Human, Digestive diseases, Intestinal disease, Inflammatory disease, Surgery
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0518221
Code Inist : 002B25G02. Création : 23/03/1999.