The results of blood cultures and clinical data of 101 neonates with 110 episodes of septicaemia during a 7-y study period were reviewed.
The overall incidence of culture-proven sepsis within the study period was 6.0 per 100 neonatal intensive care unit admissions and the mortality rate was 14%, Three groups of pathogens accounted for 70% of all isolates : coagulase-negative staphylococci (27%), aerobic Gram-negative rods (24%) and Enterococcus faecalis (19%). Group B streptococcus was the major pathogen of very early-onset septicaemia (within 24 h of birth), whereas late-onset infections were most commonly caused by coagulase-negative staphylococci.
Birthweight<1500 g. gestational age<30 weeks of gestation and early onset of symptoms within the first week of life were associated with poor prognosis.
In addition, the case fatality rate of episodes caused by Gram-negative organisms was significantly higher than that of Gram-positive bacteraemia.
Mots-clés Pascal : Unité soin intensif, Nouveau né, Homme, Prématuré, Septicémie, Infection nosocomiale, Epidémiologie, Bactérie Gram négatif, Bactérie Gram positif, Etude statistique, Incidence, Facteur risque, Mortalité, Australie, Océanie, Microbiologie
Mots-clés Pascal anglais : Intensive care unit, Newborn, Human, Premature, Septicemia, Nosocomial infection, Epidemiology, Gram negative bacteria, Gram positive bacteria, Statistical study, Incidence, Risk factor, Mortality, Australia, Oceania, Microbiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0512099
Code Inist : 002B27B10. Création : 23/03/1999.