A prospective national investigation comprising 633 extremely low birthweight (ELBW) infants born alive in the 2-y period 1990-1992 with a birthweight of <= 1000 g and gestational age of >=23 completed weeks was conducted regarding neurosensory outcome and growth.
Three-hundred and sixty-two (98%) surviving ELBW infants were assessed at a median age of 36 months, using a specially designed protocol.
At follow-up, mean height, weight and head circumference in both boys and girls were significantly lower than the reference values.
The incidence of cerebral palsy was 7% among all children and 14%, 10% and 3% in children born at 23-24,25-26 and >=27 gestational weeks, respectively.
At least one obvious handicap was present in 14%, 9% and 3% of these three groups of children, respectively.
After adjustment for gestational age, a significantly increased risk of handicap was found in children with intraventricular haemorrhage grade >=3 and/or periventricular leucomalacia and in children with retinopathy of prematurity stage >=3. The results show that more than 90% of ELBW children born at >=25 completed gestational weeks were without neurosensory handicap at 36 months of corrected age.
In infants born at 23-24 weeks of gestation, both survival and long-term outcome were less favourable.
Mots-clés Pascal : Poids naissance extrêmement faible, Développement staturopondéral, Trouble moteur, Trouble sensoriel, Evolution, Moyen terme, Age gestation, Etude statistique, Suède, Europe, Complication, Prématurité, Enfant, Homme, Pronostic, Gestation pathologie, Nouveau né pathologie, Réanimation, Handicap
Mots-clés Pascal anglais : Extremely low birthweight, Somatic growth, Motor system disorder, Sensory disorder, Evolution, Medium term, Gestational age, Statistical study, Sweden, Europe, Complication, Prematurity, Child, Human, Prognosis, Pregnancy disorders, Newborn diseases, Resuscitation, Handicap
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0510784
Code Inist : 002B27B11. Création : 23/03/1999.