Impact of exposure to insulation wool on lung function and cough in Swedish construction workers.
Objectives-To investigate whether application of insulation wool adversely affects lung volumes and increases the occurrence of symptoms of airway irritation.
Methods-Data from nationwide health check ups in 1981-93 of male construction workers born in 1955 or later were used to investigate cross sectional (n=96 004) and longitudinal (n=26 298) associations between lung volumes, vital capacity (VC), and forced expiratory volume in one second (FEV,) and exposure to insulation wool by combining a job exposure matrix (JEM) and self reported exposure.
Data on 12 month prevalence of persistent cough not associated with the common cold was available for the period 1989-92.
Potential confounding from smoking, exposure to asbestos, silica, and isocyanates, was considered in the analyses.
For those in the highest exposure category (self reported duration of exposure of =11 years, and high exposure according to the JEM) VC was on average 2.5 cl lower (95% CI - 6.5 to 1.5) than in those with no exposure.
The corresponding figures for FEV1 was - 2.4 cl (95% CI - 6.1 to 1.3).
In the longitudinal analyses, the yearly change in VC between the first and last spirometry for those in the highest exposure category was 0.50 cl (95% CI - 0.97 to 1.98) less than in the unexposed category.
The corresponding figure for FEV1 was 0.89 cl (95% CI - 0.70 to 2.06). (...)
Mots-clés Pascal : Laine verre, Isolant thermique, Industrie construction, Exposition professionnelle, Appareil respiratoire pathologie, Médecine travail, Homme, Toxicité, Epidémiologie, Suède, Europe, Etude longitudinale, Toux, Facteur risque
Mots-clés Pascal anglais : Glass wool, Thermal insulating material, Construction industry, Occupational exposure, Respiratory disease, Occupational medicine, Human, Toxicity, Epidemiology, Sweden, Europe, Follow up study, Cough, Risk factor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0504830
Code Inist : 002B03L03. Création : 19/02/1999.