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  1. Microflora of gastric biopsies from patients with duodenal ulcer and gastric cancer : A comparative study of patients from Korea, Colombia, and the United States.

    Article - En anglais

    It remains unclear why the spectrum of H. pylori-related diseases differs among different geographic regions.

    We examined the non-H. pylori contamination rates of the stomach in patients with duodenal ulcer or gastric adenocarcinoma from three different regions with different spectra of H. pylori-related diseases.

    Gastric biopsies were cultured from patients with duodenal ulcer or histologically proven gastric cancer from Seoul, Korea ; Bogota, Colombia ; and Houston, Texas.

    The frequency of non-H. pylori contamination was tallied in relation to the clinical diagnosis.

    Cultures from 247 duodenal ulcer patients and 165 patients with gastric cancer had bacterial growth.

    H. pylori was isolated from 207 (73.7%) patients with duodenal ulcer and 90 (47.1%) patients with gastric cancer (P<0.001).

    In patients with duodenal ulcer (DU) or gastric cancer (GC), the rate of positive cultures for H. pylori were not statistically different (P>0.143 for DU, P>0.190 for GC) between regions.

    The frequency of isolation ranged from 69% to 79% for DU patients and from 39% to 50% for gastric cancer patients.

    Non-H. pylori bacterial contamination was found more frequently (63%) in Colombian duodenal ulcer patients compared to 30% ulcer patients from the United States or Korea (P<0.001).

    Non-H. pylori growth occurred in 50.8-75.5% of cancer patients and was significantly lower in US patients than in patients from either Colombia or Korea (P<0.01). (...)

    Mots-clés Pascal : Carcinome, Estomac, Microflore, Ulcère, Duodénum, Etude comparative, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Contamination, Répartition géographique, Base donnée, Homme, Corée, Asie, Colombie, Amérique du Sud, Amérique, Etats Unis, Amérique du Nord, Epidémiologie, Tumeur maligne, Appareil digestif pathologie, Estomac pathologie, Intestin pathologie, Bactériose, Infection, Organisation santé

    Mots-clés Pascal anglais : Carcinoma, Stomach, Microflora, Ulcer, Duodenum, Comparative study, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Contamination, Geographic distribution, Database, Human, Korea, Asia, Colombia, South America, America, United States, North America, Epidemiology, Malignant tumor, Digestive diseases, Gastric disease, Intestinal disease, Bacteriosis, Infection, Public health organization

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0504743

    Code Inist : 002B13B01. Création : 19/02/1999.