Background and Purpose-Inconsistent information about incidence and determinants of poststroke dementia might be related to patient attrition, partly because of nonapplicability of formal neuropsychological testing to a large proportion of patients registered in a definite setting.
Methods-Using a proxy-informant interview based on ICD-10 criteria, we determined dementia at stroke onset and 1 year after stroke in the 339 patients who survived, were available for follow-up, and were not demented at stroke onset of 635 patients entered over a 1-year period in a stroke registry taken at 2 community hospitals in Florence, Italy.
Of the 339 patients, 57 (16.8%) proved to have poststroke dementia.
These patients were older, more frequently female, and more often (multivariate odds ratio, 2.35 ; 95% CI, 1.21 to 4.58) had atrial fibrillation than those without dementia.
Aphasia and the clinical features expressing the severity of the stroke event in the acute phase predicted poststroke dementia.
Conclusions-In a hospital-based nonselected series of stroke survivors, despite the use of a method with low sensitivity for defining dementia, our study confirms that dementia is a frequent sequela of stroke and is mainly predicted by stroke severity.
Certain determinants could be controlled in the prestroke phase, thus reducing its risk.
Mots-clés Pascal : Accident cérébrovasculaire, Démence, Entretien, Italie, Europe, Epidémiologie, Incidence, Facteur risque, Complication, Homme, Facteur prédictif, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Trouble neurologique
Mots-clés Pascal anglais : Stroke, Dementia, Interview, Italy, Europe, Epidemiology, Incidence, Risk factor, Complication, Human, Predictive factor, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease, Neurological disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0504244
Code Inist : 002B17C. Création : 19/02/1999.