To examine the 14-year incidence and progression of diabetic retinopathy and macular edema and its relation to various risk factors.
Population-based incidence study.
The study was conducted in an 11-county area in southern Wisconsin.
Six hundred thirty-four insulin-taking persons with diabetes diagnosed before age 30 years participated in baseline, 4-year, 10-year, and 14-year follow-up examinations.
The 14-year progression of retinopathy, progression to proliferative retinopathy, and incidence of macular edema were detected by masked grading of stereoscopic color fundus photographs using the modified Airlie House classification and the Early Treatment Diabetic Retinopathy Study retinopathy severity scheme.
The 14-year rate of progression of retinopathy was 86%, regression of retinopathy was 17%, progression to proliferative retinopathy was 37%, and incidence of macular edema was 26%. Progression of retinopathy was more likely with less severe retinopathy, being male, having higher glycosylated hemoglobin or diastolic blood pressure at baseline, an increase in the glycosylated hemoglobin level, and an increase in diastolic blood pressure level from the baseline to the 4-year follow-up. (...)
Mots-clés Pascal : Rétinopathie, Diabète insulinodépendant, Epidémiologie, Facteur risque, Incidence, Wisconsin, Etats Unis, Amérique du Nord, Amérique, Homme, Oeil pathologie, Endocrinopathie
Mots-clés Pascal anglais : Retinopathy, Insulin dependent diabetes, Epidemiology, Risk factor, Incidence, Wisconsin, United States, North America, America, Human, Eye disease, Endocrinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0490754
Code Inist : 002B21E01B. Création : 19/02/1999.