Idiopathic thrombocytopenic purpura (ITP, also known as immune thrombocytopenic purpura) in adults is principally a disease of young women.
Although in some patients the onset is acute and complete resolution occurs, in most patients, the onset is insidious and the course is chronic.
In spite of the relative frequency of ITP, there are important unresolved issues in its diagnosis and management.
For this reason, the American Society of Hematology (ASH) chose ITP as the disease topic for its initial sponsored practice guideline in 1993.
A major conclusion of the published guideline was the lack of firm evidence on which to base diagnostic procedures and management strategies.
This review describes the clinical features of ITP in adults, emphasizes the principal unresolved issues in diagnosis and management, and outlines the critical areas for future research.
Mots-clés Pascal : Purpura thrombocytopénique immun, Exploration clinique, Diagnostic différentiel, Conduite à tenir, Article synthèse, Homme, Guide pratique, Thrombocyte, Hémopathie, Immunopathologie
Mots-clés Pascal anglais : Immune thrombocytopenic purpura, Clinical investigation, Differential diagnostic, Clinical management, Review, Human, Handbook, Platelet, Hemopathy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0489699
Code Inist : 002B19C. Création : 19/02/1999.