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  1. Universal childhood hepatitis B vaccination : infants vs. preadolescents, the Canadian perspective.

    Article, Communication - En anglais

    Hepatitis B Virus : The Quest for Global Control and Eradication. Satellite Symposium. Toronto, ON, CAN, 1997/09.

    Background

    In the 1980s, populations of the United States and Canada exhibited similar and increasing incidence of hepatitis B. Vaccination programs targeted at high risk populations did not impact on overall disease incidence.

    Methods

    Hepatitis B immunization strategies in the United States and Canada were reviewed to determine their impact on vaccination coverage.

    To reduce the transmission of hepatitis B, divergent vaccination plans emerged within North America.

    The United States added hepatitis B to its universal infant immunization schedule, and Canada implemented hepatitis B immunization programs for preadolescents (9 through 13 years of age).

    Results

    To date, both strategies have markedly increased vaccination coverage among the targeted cohort.

    Hepatitis B vaccination coverage of infants rose from 8% in 1992 to 82% in 1996 in the United States.

    In Canada, hepatitis B vaccine uptake rates among preadolescents have been high, with all major provinces reporting near or greater than 90% coverage in 1996.

    Conclusions

    The incidence of acute and chronic hepatitis B in Canada should drop measurably within the decade as these protected preadolescents move into adulthood.

    In addition, the Canadian vaccine delivery infrastructure allows for the addition of new vaccines targeted for adolescents.

    Mots-clés Pascal : Hépatite virale B, Virose, Infection, Virus hépatite B, Orthohepadnavirus, Hepadnaviridae, Virus, Vaccination, Programme sanitaire, Nourrisson, Homme, Préadolescent, Canada, Amérique du Nord, Amérique, Efficacité, Appareil digestif pathologie, Foie pathologie, Prévention

    Mots-clés Pascal anglais : Viral hepatitis B, Viral disease, Infection, Hepatitis B virus, Orthohepadnavirus, Hepadnaviridae, Virus, Vaccination, Sanitary program, Infant, Human, Preadolescent, Canada, North America, America, Efficiency, Digestive diseases, Hepatic disease, Prevention

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0483417

    Code Inist : 002B05C02G. Création : 19/02/1999.