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  1. Outcome after hemorrhagic shock in trauma patients.

    Article - En anglais

    Background 

    It is essential to identify patients at high risk of death and complications for future studies of interventions to decrease reperfusion injury.

    Methods 

    We conducted an inception cohort study at a Level I trauma center to determine the rates and predictors of death, organ failure, and infection in trauma patients with systolic blood pressure <= 90 mm Hg in the field or in the emergency department.

    Results 

    Among the 208 patients with hemorrhagic shock (blood pressure <= 90 mm Hg), 31% died within 2 hours of emergency department arrival, 12% died between 2 and 24 hours, 11% died after 24 hours, and 46% survived.

    Among those who survived = 24 hours, 39% developed infection and 24% developed organ failure.

    Increasing volume of crystalloid in the first 24 hours was strongly associated with increased mortality (p=0.00001).

    Conclusion 

    Hemorrhage-induced hypotension in trauma patients is predictive of high mortality (54%) and morbidity.

    The requirement for large volumes of crystalloid was associated with increased mortality.

    Mots-clés Pascal : Choc, Association, Traumatisme, Hémorragie, Réanimation, Pronostic, Epidémiologie, Facteur risque, Complication, Insuffisance organique multiple, Mortalité, Morbidité, Homme, Appareil circulatoire pathologie, Vaisseau sanguin pathologie

    Mots-clés Pascal anglais : Shock, Association, Trauma, Hemorrhage, Resuscitation, Prognosis, Epidemiology, Risk factor, Complication, Multiple organ failure, Mortality, Morbidity, Human, Cardiovascular disease, Vascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0480673

    Code Inist : 002B27B01. Création : 19/02/1999.