Study objective-Mortality over 25 years has been low in the Italian and very low in the Greek cohorts of the Seven Countries Study ; factors responsible for this particularity were studied in detail.
Participants and settings-1712 Italian and 1215 Greek men, aged 40-59 years, cohorts of the Seven Countries Study, representing over 95% of the populations in designated rural areas.
Design-Entry (1960-61) data included age, systolic blood pressure (SBP), smoking habits, total serum cholesterol, body mass index (BMI), arm circumference, vital capacity (VC), and forced expiratory volume in 314 seconds (FEV) ; the same data were obtained 10 years later.
Multivariate Cox analysis was performed with all causes death in 25 years as end point.
Main results-Italian men had higher entry levels of SBP, arm circumference, BMI, and VC ; Greek men had higher cholesterol levels, smoking habits, and FEV.
Mortality of Italian men was higher throughout ; at 25 years cumulative mortality was 48.3% and 35.3% respectively.
Coronary heart disease and stroke mortality increased fivefold in Italy and 10-fold in Greece between years 10 and 25.
The only risk factor with a significantly higher contribution to mortality in Italian men was cholesterol.
However, differences in entry SBP (higher in Italy) and FEV (higher in Greece) accounted for, according to the Lee method, 75% of the differential mortality between the two populations. (...)
Mots-clés Pascal : Mortalité, Taux, Facteur risque, Epidémiologie, Evolution, Etude comparative, Adulte, Homme, Mâle, Italie, Europe, Grèce
Mots-clés Pascal anglais : Mortality, Rate, Risk factor, Epidemiology, Evolution, Comparative study, Adult, Human, Male, Italy, Europe, Greece
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0477246
Code Inist : 002B30A01A2. Création : 19/02/1999.