Indwelling urinary catheters are implicated in most cases of nosocomial urinary tract infection.
Silver-coating of catheters may reduce the risk of these infections ; however, trials have provided mixed results.
We performed a meta-analysis to estimate the effectiveness of silver-coated urinary catheters.
Published or unpublished articles were sought using MEDLINE, reference review, and correspondence with original authors, catheter manufacturers, and experts.
Trials using silver-coated urinary catheters in the treatment group and uncoated urinary catheters in the control group were included.
Bacteriuria, as evaluated by urine culture, was the outcome variable used to indicate urinary tract infection.
Summary odds ratios (OR) and 95% confidence intervals (CI) were calculated using Mantel-Haenszel methods with a fixed-effects model.
Of 117 reports retrieved, eight trials with a total of 2,355 patients satisfied inclusion criteria.
The summary OR for urinary tract infection was 0.59 (95% CI, 0.42 to 0.84) indicating a significant benefit in the patients receiving silver-coated catheters.
A test of heterogeneity, however, indicated that the odds ratios varied significantly among studies.
Silver alloy catheters (OR=0.24 ; 95% CI, 0.11 to 0.52) were significantly more protective against bacteriuria than silver oxide catheters (OR=0.79 ; 95% CI, 0.56 to 1.10). (...)
Mots-clés Pascal : Infection nosocomiale, Voie urinaire, Prévention, Cathéter, Argenture, Métaanalyse, Analyse coût efficacité, Analyse statistique, Article synthèse, Revue bibliographique, Homme, Infection, Appareil urinaire pathologie, Traitement instrumental, Economie santé
Mots-clés Pascal anglais : Nosocomial infection, Urinary tract, Prevention, Catheter, Silver coating, Metaanalysis, Cost efficiency analysis, Statistical analysis, Review, Bibliographic review, Human, Infection, Urinary system disease, Instrumentation therapy, Health economy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0471315
Code Inist : 002B14E02. Création : 19/02/1999.