Recent studies have suggested that weight loss in middle-aged persons antecedes increased mortality.
Therefore, the authors sought to examine the association between changes in body weight and subsequent mortality, according to self-reported dieting status.
The authors followed 9,228 men aged 40-65 years in 1963, for whom weight changes between 1963 and 1968 were recorded and extensive clinical, anthropometric, biochemical, and dietary assessments were made.
Of these men, 2,471 reported being on a diet when first examined in 1963, and 636 were dieting primarily to lose weight.
Mortality follow-up covered an 18-year period (1968-1986), Men who lost 5 kg or more between 1963 and 1968 ( « extreme weight losers ») exhibited the following age-pooled risks of mortality relative to the stable weight group :
for total mortality, 1.36 (95% confidence interval (Cl) 1.20-1.55) ;
for all cardiovascular disease mortality, 1.40 (95% Cl 1.16-1.69) ;
for all non-cardiovascular disease mortality, 1.33 (95% Cl 1.11-1.59) ;
for coronary heart disease mortality, 1.55 (95% Cl 1.25-1.93) ;
and for cancer mortality, 0.90 (95% Cl 0.65-1.24).
After adjustment for differences in coronary heart disease risk factor levels and morbidity between these groups at the end of the weight change period (1968), the excess risks associated with extreme weight loss declined by approximately one third. (...)
Mots-clés Pascal : Perte poids, Poids corporel, Mortalité, Epidémiologie, Facteur risque, Adulte, Homme, Vieillard, Mâle, Israël, Asie
Mots-clés Pascal anglais : Weight loss, Body weight, Mortality, Epidemiology, Risk factor, Adult, Human, Elderly, Male, Israel, Asia
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0467424
Code Inist : 002B30A01A2. Création : 19/02/1999.