The study covered 52 women, aged 19-30 years, who had previously taken home-made poppy preparations.
In seven ofthem we diagnosed opium use (F 11.11 according to ICD-10) and 45 had opium abuse (F 11.21).
All were detained in penitentiaries for 2-23 months.
The control group consisted of 20 healthy females.
A significant frequency of brain stem and extrapyramidal disturbances was found in the opium abuse group.
Brain stem signs included tendon anisoreflexia (100-2%), nystagmus (87±5%), ataxia (87±5%) and corneal hyporeflexia (48± 7%). Among the most frequent extrapyramidal disturbances were a positive pushing test (90±4%) ; test with pendular swinging of the legs (85±5%) and hand tremor (82±7%). Statistical analysis revealed a relationship between the degree of extrapyramidal system damage and duration of opiate dependence.
Mots-clés Pascal : Opium, Opiacés, Toxicomanie, Extrapyramidal syndrome, Tronc cérébral syndrome, Homme, Femelle, Dépendance, Voie intraveineuse, Durée, Evolution, Corrélation, Rémission, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Milieu carcéral, Epidémiologie
Mots-clés Pascal anglais : Opium, Opiates, Drug addiction, Extrapyramidal syndrome, Brain stem syndrome, Human, Female, Dependence, Intravenous administration, Duration, Evolution, Correlation, Remission, Nervous system diseases, Central nervous system disease, Cerebral disorder, Carceral environment, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0465897
Code Inist : 002B03D. Création : 19/02/1999.