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  1. cagA-positive Helicobacter pylori and risk for developing gastric carcinoma in Brazil.

    Article - En anglais

    To evaluate a possible association between infection with cag A-positive strains and gastric carcinoma increased risk we studied 119 Helicobacter pylori-positive patients with gastric carcinoma and 119 matched controls.

    The presence of cag A gene was investigated by PCR in H. pylori isolates and in gastric biopsy specimens.

    A significant association was found between cag A-positive status and distal gastric carcinoma for both the intestinal and diffuse types of tumor for both males and females.

    On the other hand, no association was observed between cag A-positive status and proximal gastric carcinoma.

    Mots-clés Pascal : Carcinome, Estomac, Facteur risque, Epidémiologie, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Souche, Gène, Etude cas témoin, Brésil, Amérique du Sud, Amérique, Homme, Tumeur maligne, Appareil digestif pathologie, Estomac pathologie, Génétique, Gène cagA

    Mots-clés Pascal anglais : Carcinoma, Stomach, Risk factor, Epidemiology, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Strain, Gene, Case control study, Brazil, South America, America, Human, Malignant tumor, Digestive diseases, Gastric disease, Genetics

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0464264

    Code Inist : 002B13B01. Création : 19/02/1999.